Most single amino acid substitutions (SAASs) lack experimental annotation of their functional impact. SNPdbe is a database and a webinterface that is designed to fill the annotation gap left by the high cost of experimental testing for functional significance of protein variants. It joins related bits of knowledge, currently distributed throughout various databases, into a consistent, easily accessible, and updatable resource. We currently cover over 155,000 protein sequences which come from more than 2,600 organisms. Overall we reference more than one million SAASs consisting of natural variants, SAASs from mutagenesis experiments and sequencing conflicts.
For more details, please refer to our statistics overview.
|2012-03-05:||Updated to human dbSNP release b135.|
|2012-02-21:||Result file now contains dbSNP and SwissVar ids.|
|2012-02-20:||Updated to recent Swiss-Prot release (2012-01).|
|2012-02-13:||SNPedia references our service.|
|2012-02-09:||Search results are now accessible through a direct link.|
|2012-08-13:||Several website bugs fixed.|
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