Services

Complete Sequence Analysis

Service for sequence analysis and Protein structure Prediction

See the official Rostlab GitHub page for the latest updates and tools. Some tools listed below may be deprecated or discontinued.

Aquaria	Identify relevant exerimental 3D structures and generate insight from structures and annotations
AGAPE	Fold recognition without folds: Improved and generalized method for sequence-profile and profile-profile comparisons using sequence and predicted 1D structure
CHOP	CHOPping proteins into structural domain-like fragments
ConSequenceS	Consensus Sequence Searches with PSI-BLAST
DSSPcont	Continuous assignment of Protein Secondary Structure
Meta Disorder (MD)	Protein disorder prediction based on orthogonal sources of information
NORSp	Prediction of NOn-Regular Secondary Structure (NORS)
PROFbval	Prediction of protein flexibility and rigidity prediction from sequence
PROFcon	Prediction of inter-residue contacts
ProfTMB	Prediction of TransMembrane Beta Barrels
TMH-Benchmark	Evaluate new methods for Trans-Membrane Helix prediction
UCON	Prediction of natively unstructured regions through contact maps

ECGO	Prediction of Enzymatic Activity of a Protein Sequence in Terms of Enzyme Commission (EC) Numbers
DISIS	Prediction of residues involved in DNA binding
PPSites2 (PROFIsis)	Prediction of residues involved in external protein-protein interactions.
LOCnet	De novo prediction of protein sub-cellular localization
LOCtree	Prediction of sub-cellular LOCalization for structural genomics targets
LOCtree2	Prediction of sub-cellular localization for all proteins in all domains of life
PiNat	Method for assessing the validity of yeast two hybrid experiments results
predictNLS	Prediction and analysis of Nuclear Localization Signals
SNAP	Evaluates the effects of single amino acid substitutions on protein function

Creating sequence-Unique Protein databases

Mining Natural Language text for PROTein names and their UniProt-IDs

CellCycleDB	Database collecting and annotating proteins involved in cell-cycle control
Epitome	Database of structure-inferred antigenic epitopes.
ERGolgiDB	Archive of proteins from endoplasmic reticulum and Golgi apparatus
LocDB	LocDB is a expert curated database that collects experimental annotations for the subcellular localization of proteins in Human (Homo sapiens) and Weed (Arabidopsis thaliana)
NLSdb	Database of nuclear localization signals (NLSs) and of nuclear proteins targeted to the nucleus by NLS motifs
NMPdb	NMP-db is a database of nuclear matrix associated proteins
SNPdbe	SNPdbe is a rich database of nsSNPs augmented with effects (experimentally derived and predicted), disease associations and more

TMHeval	Evaluation of transmembrane helix prediction methods: dataset and evalutation scores
OMIA	Predicted molecular effects tell stories about system level of disease