Christian Schaefer

(Dipl.-Bioinf. Univ.)

PhD candidate at TUM Computer Science and GSISH graduate school

Research Interest

C. Schaefer, B. Rost
Predict impact of single amino acid change upon protein structure
BMC Genomics, accepted
C. Schaefer, Y. Bromberg, D. Achten, B. Rost
Disease-related mutations predicted to impact protein function
BMC Genomics, accepted
C. Schaefer, A. Meier, B. Rost, Y. Bromberg
SNPdbe: Constructing an nsSNP functional impacts database
Bioinformatics, 2011
A. Schlessinger, C. Schaefer, E. Vicedo, M. Schmidberger, M. Punta, B. Rost
Protein disorder - a breakthrough invention of evolution?
Current Opinion in Structural Biology, 2011
C. Schaefer, A. Schlessinger, B. Rost
Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be.
Bioinformatics, 2010

ISMB 2011, Vienna, Austria:
Talk: “Can we predict structural change upon point mutation?” (SNP SIG)
Poster: “Comprehensive nsSNP database with predictions and annotations of impact”
3rd GSISH symposium on biomedical informatics, Spitzingsee, Germany:
Talk: “Predicting the structural effect of point mutations in proteins - Towards personalized medicine”
ISMB 2010, Boston, USA:
Poster: “Protein secondary structure is robust under artificial evolution while protein disorder is not.”
7th annual Rocky Mountain Bioinformatics Conference 2009, Aspen, USA:
Poster: “Protein secondary structure is robust under artificial evolution while protein disorder is not.”

Summer term 2012:	Hauptseminar Bioinformatik Proseminar Bioinformatik
Winter term 2011/12:	Hauptseminar Bioinformatik
Summer term 2011:	Protein Prediction I (Exercise) Hauptseminar Bioinformatik
Winter term 2010/11:	Protein Prediction II (Exercise) Hauptseminar Bioinformatik
Summer term 2010:	Protein Prediction I (Exercise) Hauptseminar Bioinformatik
Supervised theses / internships:	Vivien Klose, Master Thesis: Protein function prediction through gene ontology Shen Wei, Bachelor Thesis: Extracting residues involved in binding from PDB Peter Hoenigschmid, Master Thesis: DNA/RNA binding site prediction Yannick Mahlich, Bachelor Thesis: Feature construction and selection for predicting structural change upon point mutation in proteins (done) Alice Meier, Internship: Implementation of a web frontend for the access of a SNP-to-phenotype database Peter Hoenigschmid, Internship: Reimplementation of PROFPhd (done) Manfred Roos, Internship: In-silico mutagenesis of all human proteins using SNAP

04/2010 -	present:	Research assistant, Rostlab, Technical University Munich, Germany
04/2009 -	04/2010:	Research assistant, Rostlab, Columbia University, New York City, USA
10/2003 -	10/2008:	Studies of Bioinformatics in Munich, Germany
		German diploma degree (high distinction), M.Sc. equivalent
		Thesis at German Cancer Research Center (DKFZ) Heidelberg, Supervisors: Dr. Michael Pawlita (DKFZ), Prof. Dr. Stefan Kramer (TUM)
		(Antibody patterns in H.pylori infection and associated gastric carcinoma)

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Last updated: 2012-05-12