Index Page Index
Page
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| The program |
Download
a command-line version of uniqueProt (Linux and NEW!!: WINDOWS)
read the help
pages
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| Input and output
of the program |
UniqueProt takes a submitted protein list and derives a list
of sequence-unique proteins by first comparing the sequences with BLAST and
secondly using a greedy algorithm to get a representative
set from the BLAST output reaching maximum coverage and minimum redundancy
for the representative set. The BLAST-alginment can be circumvented by submitting a pairwise
alignment file produced by more accurate alignment programs such as PSI-BLAST or water.
The number of built sets/families depends on
the HSSP-value, which the program needs as a cutoff parameter
(read more about HSSP-values and the theory in the paper to this
service).
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Read the
paper
Cite this page |
When using output from uniqueProt please refer to:
Mika, S.; Rost, B.
UniqueProt: creating representative protein-sequence sets.
Nucleic Acids Res. 2003;31(13):3789-3791.
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| Contact |
E-mail: mika@cubic.bioc.columbia.edu
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| From here |
 pppppppppp pppppppppp
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©2003, Sven Mika &
Burkhard Rost
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